Lawrence Livermore Nationwide Laboratory has put in a brand new high-performance computing (HPC) cluster with sufficient reminiscence and storage for data-intensive COVID-19 analysis and pandemic response.
Funded by the federal Coronavirus Help, Reduction and Financial Safety (CARES) Act, the “huge reminiscence” cluster, referred to as Mammoth, can be used for genomics evaluation, nontraditional HPC simulations, and graph analytics required by scientists engaged on COVID-19, together with the event of antiviral medicine and designer antibodies.
“The power of large-memory techniques to combine genomic evaluation with large-scale machine studying for predictive modeling of therapeutic response can be vital for accelerating the event of efficient new therapeutics,” mentioned Jim Brase, the lab’s deputy affiliate director for computing.
“Mammoth can be integral for creating new instruments to fight COVID-19, but additionally for quick response in a future pandemic,” Brase mentioned.
Mammoth consists of 64 nodes, every with two 64-core CPUs, options high-memory bandwidth and offering two terabytes of random-access reminiscence and almost 4 terabytes of nonvolatile reminiscence. The additional reminiscence is crucial for COVID-19 researchers, who should sift via large databases of data.
“It’s thrilling to see a direct connection between know-how and the science being finished to enhance and even save lives,” mentioned Dan McNamara, senior vice chairman with Superior Micro Gadgets, a associate in Mammoth with LLNL. “AMD is proud to help the very important analysis being finished by the workforce at LLNL with Mammoth together with our know-how companions at Supermicro and Cornelis Networks.”
LLNL researchers have begun making use of Mammoth to the genome of the SARS-CoV-2 virus that causes COVID-19, utilizing the computing cluster to investigate how the virus evolves and simulating how its construction adjustments once they introduce mutations.
Mammoth helps scale back the time it takes to carry out some varieties of genomic evaluation from a couple of days to some hours, based on the researchers. Mammoth’s reminiscence sources and quite a few cores are additionally aiding within the design of modified antibodies.