A group of researchers from Kaunas College of Know-how and Lithuanian College of Well being Sciences proposed a non-invasive methodology for detection of melanoma. A patented computer-aided diagnostic system developed by Lithuanian scientists proved to be greater than 90% correct in detecting malignancy in diagnostic photos of pores and skin lesions acquired from 100 sufferers.
In Europe, melanoma is the fifth most typical kind of most cancers and is the most important explanation for dying from pores and skin most cancers. Northern Europe shows the most important age-standardised fee mortality of three.8 per 10,000 within the area, with an incidence of 23.4.
Excision of a major tumour stays important in diagnosing melanoma, and the choice for the operation is mostly based mostly on the dermatoscopic analysis of the lesion. Nonetheless, the accuracy of melanoma medical prognosis is barely at 65% and strongly depends on the expertise of the physician-dermatologist finishing up the evaluation.
“The novelty of our methodology is that it combines diagnostic info obtained from completely different non-invasive imaging applied sciences similar to optical spectrophotometry and ultrasound. Based mostly on the outcomes of our analysis, we will affirm that the developed automated system can complement the non-invasive diagnostic strategies at present utilized within the medical apply by effectively differentiating melanoma from a melanocytic mole”, says Professor Renaldas Raisutis, head of the group behind the analysis at Kaunas College of Know-how.
Within the research, carried out by the researchers of two Lithuanian universities, diagnostic photos of pores and skin lesions acquired from 100 completely different sufferers had been evaluated. By evaluating and analysing complicated knowledge on pores and skin tumours recorded by completely different strategies, the researchers had been capable of develop a novel diagnostic system, differentiating melanoma from a benign nevus with accuracy larger than 90%.
“An environment friendly prognosis of an early-stage malignant pores and skin tumour may save essential time: extra sufferers could possibly be examined and extra of them could possibly be saved”, says Prof Raisutis.
In response to Prof Raisutis, the novel diagnostic system is firstly aimed toward medical professionals; he estimates that the value of the ultimate product is likely to be reasonably priced even for smaller medical establishments. Nonetheless, the group can be desirous about the options for particular person use at house.
Following the analysis, the prototype of the know-how was developed, and the medical analysis is being carried out complying with the necessities of the protocol for the medical analysis confirmed by the regional bioethics committee.
The invention was patented in Lithuania (Patent No. LT6670B) and the patent functions filed for Patent Cooperation Treaty and the US Patent and Trademark Workplace.
The above-described methodology and know-how had been developed inside the framework of the undertaking “SkinImageFusion: Advanced Evaluation Technique of Spectrophotometric and Ultrasound Information for the Computerized Differential Analysis of Early Stage Malignant Pores and skin Tumours”, funded by Lithuanian Analysis Council and carried out by a joint group of Kaunas College of Know-how and Lithuanian College of Well being Sciences (the latter headed by Professor Skaidra Valiukeviciene) in 2017-2020. Three doctoral dissertations had been defended on the premise of this analysis.
Reference: Tiwari KA, Raišutis R, Liutkus J, Valiukevičienė S. Diagnostics of Melanocytic Pores and skin Tumours by a Mixture of Ultrasonic, Dermatoscopic and Spectrophotometric Picture Parameters. Diagnostics. 2020;10(9)632. doi:10.3390/diagnostics10090632
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